How does gastric sleeve surgery affect ghrelin?

How does gastric sleeve surgery affect ghrelin

We have been told that the ghrelin hormone is responsible for a few things, including hunger and appetite regulation. But what does gastric sleeve surgery affect ghrelin? The answer may surprise you! This article will explore how this common weight-loss procedure affects the production of ghrelin.  

What is ghrelin, and what does it do?

Ghrelin is a hunger hormone and is produced by ghrelin cells in the stomach. It acts on receptors found mainly in the hypothalamus to increase hunger, gastric emptying, and gastrointestinal motility.

The major function of ghrelin is stimulating hunger (a need to eat). As a result, people with higher levels tend to weigh more and have a larger body mass index (BMI). Ghrelin has been shown to be the only known appetite-stimulating hormone, as deficiencies in ghrelin and/or its receptor cause severe (but reversible) weight loss and decreased food intake.

What is gastric sleeve surgery, and what does it do?

Gastric bypass surgery is a type of weight loss surgery where the stomach is divided into a small upper pouch and a larger lower “remnant” pouch and then attached to an opening (connection) in the middle. In addition, the surgeon may also connect the small intestine to that connection. This limits how much food can enter your stomach at one time, reducing your hunger. The food you eat bypasses the rest of your stomach and most of your small intestine.

How does post gastric sleeve surgery affect ghrelin?

In the process of taking out a large portion of the stomach, ghrelin cells are also taken out. This means that from then on, individuals who have undergone gastric sleeve surgery will no longer be able to produce ghrelin and thus will not feel hunger or eat as much as before. In this sense, it acts just like bariatric surgery. Thus, there is a direct relationship between ghrelin and gastric sleeve.

This may also interest: What Is the Size of The Stomach After Gastric Sleeve Surgery?

The role of ghrelin in weight loss

Before gastric sleeve surgery, patients will need to eat normally (feel hungry) to reach a minimum number of calories. However, hunger after gastric sleeve will change. After a Gastric Sleeve Surgery in Roswell, NM, they can then reduce their portions and intake of food because their hunger won’t be as much as before due to the removal of ghrelin cells.

A study has shown that obese individuals had higher levels of ghrelin than their leaner counterparts. It also states that suppressing the secretion of ghrelin can lead to decreased appetite and caloric intake, leading to weight loss.

While gastric sleeve surgery can suppress the production of ghrelin, it does not mean that one will lose weight automatically. Lifestyle changes such as increasing physical activity and eating healthier foods are still important to achieve weight loss. If you’re considering weight loss surgery but have questions about how this procedure will affect your appetite, talk to a doctor for personalized advice on whether or not this could be right for you.

Denny Rush

Denny Rush